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Capillary Electrophoresis with Mass Spectrometry: Applications to Metabolomic Analysis

[ Vol. 1 , Issue. 2 ]

Author(s):

Katie Yan, Jeffrey Brumbaugh, Jeremy Barrett, Sarah Jung and Shen Hu   Pages 121 - 127 ( 7 )

Abstract:


The use of capillary electrophoresis with mass spectrometry (CE-MS) for metabolomic analysis has substantially increased in recent years. This hyphenated technique takes full advantage of the high separation efficiency of CE and the identification capability of MS, providing a powerful tool for rapid analysis and identification of metabolites in complex biological samples. This article focuses on an overview of some recent applications of CE-MS in metabolomics studies. We also discuss the techniques for the coupling of CE with MS and the potential of 2-D CE-MS for metabolomic analysis.

Keywords:

CE-MS, 2-D CE, metabolomics.

Affiliation:

Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095, USA.



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